Posted by: Jayme | May 7, 2008


NICHD Neonatal Research Network (NRN):
Extremely Preterm Birth Outcome Data

Based on the following characteristics:

Estimated outcomes* for infants in the NRN sample are as follows:

Outcomes Outcomes for All Infants Outcomes for Mechanically Ventilated Infants
Survival 58% 62%
Survival Without Profound Neurodevelopmental Impairment 44% 47%
Survival Without Moderate to Severe Neurodevelopmental Impairment 29% 31%
Death 42% 38%
Death or Profound Neurodevelopmental Impairment 56% 53%
Death or Moderate to Severe Neurodevelopmental Impairment 71% 69%

* These estimates are based on standardized assessments of outcomes at 18 to 22 months of infants born at NRN centers between 1998 and 2003; infants were 22 to 25 weeks, between 401 and 1,000 grams at birth. Infants not born at a Network center and Infants with a major congenital anomaly were excluded. The first column of estimates is based on findings for all 4,446 infants in the study. The second column of estimates is based only on the 3,702 infants who received intensive care. The rate of a given outcome had intensive care been attempted for all infants is likely to be intermediate between these two estimates. Sonographic estimates of fetal weight may be used in anticipating birth weight, while assessing the minimum and maximum likely birth weight consistent with the potential error of sonographic estimates.

These data are not intended to be predictive of individual outcomes. Instead, the data provide a range of possible outcomes based on specific characteristics. Researchers conducted their analysis at level III NICUs, specialized facilities offering medical care for newborn infants. The statistics may not apply to infants born at lower level NICU facilities. Please note that these data provide only possible outcomes, and that the estimates apply only at birth. It is also important to note that outcomes change over time and that they differ for a variety of reasons, including NICU features, patient population, obstetric complications and care, and care after discharge home.

If you choose to use these data to determine possible outcomes, please remember that the information provided is not intended to be the sole basis for care decisions, nor is it intended to be a definitive prediction of outcomes if intensive care is provided. It is important for users to keep in mind that every infant is different, and that factors beyond these standardized assessments may influence infant outcomes.


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